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KMID : 0371320000590010133
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Journal of the Korean Surgical Society
2000 Volume.59 No. 1 p.133 ~ p.136
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Treatment of Acute Colonic Pseudo-obstruction (Ogilvie's Syndrome) with Intravenous Neostigmine
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홍부환/Boo Hwan Hong
이선일/류근원/김선한/구범환/문홍영/Sun Il Lee/Keun Won Ryu/Sun Han Kim/Bum Hwan Goo/Hong Young Moon
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Abstract
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Acute colonic pseudo-obstruction is a functional disorder that closely mimics a mechanical large-bowel obstruction. Two such patients were treated by pharmacological manipulation of the parasympathetic innervation to the colon with intravenous
neostigmine infusion. The two responded to treatment with passage with flatus and stool within several minutes with complete resolution of the symptoms, although the first patient required two additional infusions and the second patient required
one
additional infusion for subsequent recurrence. Dizziness occurred in one patient, and no other serious side effects were apparent. This pharmacological approach to the management of acute colonic pseudo-obstruction is suggested as an alternative
to
the
other treatment options of colonoscopic decompression or surgery when conservative management has failed.
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KEYWORD
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